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Mark Gregory Iles (April 8, 1960 – August 15, 2025) was an American novelist who lived in Mississippi. He published seventeen novels and one novella, spanning a variety of genres.
In 2002, Iles wrote the screenplay 24 Hours from his novel of the same name. Rewritten by director Don Roos, it was renamed Trapped. Iles then rewrote the script during the shoot, at the request of the producers and actors.
In 2011, Iles was seriously injured in a traffic accident on U.S. Route 61 near Natchez. He sustained life-threatening injuries, including a ruptured aorta. He was put into an induced coma for eight days, and lost his right leg below the knee. During his three-year recovery, he wrote three volumes of a trilogy set in Natchez, Mississippi, and featuring former prosecutor Penn Cage.
Iles was a member of the literary musical group The Rock Bottom Remainders, which includes or has included authors Dave Barry, Ridley Pearson, Stephen King, Scott Turow, Amy Tan, Mitch Albom, Roy Blount, Jr., Matt Groening, and James McBride. In July 2013, he co-authored Hard Listening (2013) with the group. The ebook combines essays, fiction, musings, email exchanges and conversations, photographs, audio and video clips, and interactive quizzes to give readers a view into the private lives of the authors/musicians.
Iles was diagnosed with multiple myeloma, a form of blood cancer, in 1996. By the early 2020s, the cancer had progressed substantially, leaving him requiring a wheelchair; he underwent a stem cell transplant before the publication of his final novel, Southern Man (2024). He died from the disease at his Natchez home on August 15, 2025, at the age of 65.
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Categories: 1960 Births, 2025 Deaths, 20th-century American Male Writers, 20th-century American Novelists, 21st-century American Male Writers, 21st-century American Novelists, American Amputees, American Male Novelists, American Thriller Writers, American Wheelchair Users, Barry Award Winners, Deaths From Cancer In Mississippi, Deaths From Multiple Myeloma In The United States, Novelists From Mississippi, People From Natchez, Mississippi, Rock Bottom Remainders Members, University Of Mississippi Alumni, Writers From Stuttgart
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